1. Multivalent import platform(MVIP)

      Multivalent import platform(MVIP)

      Fully independent intellectual property rights. Kylonova's Multivalent Import Platform (MVIP) is a specific delivery system for hepatic disease treatments constructed using the hepatic parenchymal cells of the Asialoglycoprotein receptor (ASGPR).

      General Formula:

      (X-L)n-B-D-T 

      Wherein:

      ※        X is a target-specific ligand

      ※        L is a branch of a sterically stabilized structure

      ※        B is a connector

      ※        D is a linker

      ※        T is a drug

      ※        n is an integer from 1 to 15


       

      Multivalent Import Platform (MVIP) has the following features:

      ●  It has been applied to siRNA drugs. Pre-clinical subcutaneous injection test has been finished. It has active liver targeting, stability and good biodegradability.

      ●  Applicable to small molecule drugs, the pre-clinical intestinal drug administration has been verified, which can avoid the whole-body intake of drugs and reduce the toxic side effects on other organs.

      ●  Low production costs, can be produced in bulk, and sold commercially.